Felix Hoffmann

This biographical sketch of Felix Hoffmann has been reproduced from the book Pharmaceutical Achievers. The main scientific points discussed in the reading are the concept of synthesis and the concept of drug design. The reading stresses that in Hoffmann's time scientists were beginning not only to build new molecules, but to attempt the design of molecules not found in nature for specific medicinal purposes. This practice continues in a much more highly sophisticated form to this day in the pharmaceutical industry and in other fields of chemistry as well. The reading also describes Hoffmann's development of heroin. This can be used to illustrate the often unforeseen consequences of a discovery, and to raise questions concerning the responsibilities and ethical questions faced by scientists.

Relevant National Science Education Standards

Physical Science — The reading involves the molecular nature of matter and chemical reactions in relation to synthesis.

Science and Technology — The technology of chemistry applied to drug design is central to the reading.

Science in Personal and Social Perspectives — The reading tells the story of science being used to face a health challenge, that of pain.

History and Nature of Science — The reading gives historical perspective and emphasizes science as a human endeavor.