Title and Description Page
Early Years 1
Born in MacDill Air Force Base in Florida. Always liked science. Pond water creatures. Schools not good. Read a lot. Taught himself science. Built analog computer at age of about ten. No interest in religion. Sent to Phillips Academy Andover for high school. Loved Andover. Timesharing computing from Dartmouth College just beginning; Church able to access Dartmouth’s files.
College Years 3
Entered Duke University. Majored in zoology and chemistry. Had keys to chemistry lab. Finished (failed out) in two years. Summer course in quantum physics at Massachusetts Institute of Technology. Job in Sung-Hou Kim’s crystallography lab. Intersection of computers and biology perfect for him. Five papers.
Graduate School and Postdoc Years 8
Walter Gilbert’s lab at Harvard University. Liked sequencing. Getting machine to work in crystallography rotation. Polony sequencing. Multiplexing. Short stint at Biogen Research Corporation. Accepts postdoc at University of California, San Francisco, working in Gail Martin’s lab. Interested in interface between academia and commerce. In forefront of genomics. Leaves early to follow future wife, Ting Wu, to Boston, Massachusetts.
Harvard Medical School Years 22
Assistant professorship in Genetics; Gary Ruvkun’s lab. Howard Hughes Medical Institute. U.S. Department of Energy grant. Wife’s career culminating in tenured full professorship at Harvard Medical School. Patents and licensing. Sequencing and synthesis. Functional and comparative genomics. Systems biology a “fantasy.” Applying crystallographic insights into automation and computing to different fields of biology. Founding companies. Connection between research and clinical medicine may lead to personal genomics.