Title and Description Page
Childhood and Early Career 1
Growing up in the Philadelphia area. Attending Malvern Preparatory School. Interest in the life sciences. Studying physical therapy at West ChesterUniversity. Service during the Vietnam War. Early marriage and first child. First marketing and sales job with Blood Plasma and Components. Transferring to Abbott Laboratories. Radioimmunassay technologies. Taking over the immunoassay business for Corning Glass Works. Immophase technology. The free T-4 test. Leaving Corning for General Electric's CT business.
Centocor's Origins 6
Monoclonal antibodies. Introductions to Ted Allen, Michael Wall, Hilary Koprowski, and Hubert Schoemaker. The 17-A antibody. The hepatitis testing kit. The 19-9 antibody. Centocor's early business plan. Working with Centocor while at G.E. Being asked to head Centocor's marketing department. Moving back to Philadelphia from Wisconsin. Early impressions of Centocor. Contrast between Centocor and Hybritech's missions. Running the diagnostics business. Dividing Centocor into a diagnostics and a therapeutic company.
The Centoxin Era 13
Hiring James Wavle as co-CEO. R&D partnerships. Hiring Liz Tallett to head the pharmaceutical branch of Centocor. Expansion of infrastructure and employees. Company dynamics. Centoxin. Clinical trials. Lawsuit with XOMA. Alternate products (17-1A and ReoPro). Issues with the FDA.
The Centocor Comeback 22
Taking over as CEO. Centocor's fundraising activities. Partnership with Eli Lilly. ReoPro. 17-1A (Panorex). Remicade. Sale to Johnson and Johnson.
Johnson and Johnson and The Biotech Industry 40
quot;Running J&J's Development Corporation. Anticipating retirement in 2007. Philadelphia-area biotech development. Geographic assistance in biotech development. Regulatory issues. The Ben Franklin Partnership.
Personal Life 44
Holveck's wife, Patricia Ann. Daughters Lisa Marie and Jennifer Christine, and their children.