Title and Description Page
Childhood and Early Influences 1
Parents, grandmother, and siblings. Influence of Jerry Creighton and Louis Fieser. An entrepreneurial father and a Quaker tradition. The George School, science courses, and sports.
Undergraduate Education 6
The honors program at Swarthmore. Other chemistry students. Edward H. Cox. Mathematics, history and philosophy of science. "Ducky" Holmes and Brand Blanchard.
Graduate Study at Harvard University 11
Becoming a chemist. Coursework with Kohler. Research with Fieser on reaction mechanisms. Kistiakowsky. The impact of Huckel's work. Electrostatic versus resonance effects. Colleagues and ambience at Harvard.
Work at the University of Illinois 18
A post-doc with Roger Adams. Teaching organic chemistry. Speed Marvel. Academic salaries. Early research problems. Polymerization.
The Emergence of Physical Organic Chemistry 22
The conference at Notre Dame on organic mechanisms. The impact of Hammett's book. Resonance factors. Paul Bartlett. World War II and the unification of physical organic chemistry.
Wartime Research 27
Electrophilic substitution and resonance effects. Water decontamination and the behavior of mustards. Paul Bartlett, Saul Winstein, and other colleagues. Antimalarials and Roy Roberts.
From Illinois to Notre Dame 34
Teaching at Illinois. The Notre Dame appointment. Colleagues at Illinois and Notre Dame. Bob Woodward.
Recent Research 40
Mustards and chemotherapy. DNA alkylation. RNA synthesis and evolution.
The Practice of Physical Organic Chemistry 45
A changing discipline. Some unsolved problems. Biochemical and solid state applications. Rubber research and polypropylene oxides. Building a department at Notre Dame. Chemistry at Penn.
Political Ventures 52
United World Federalists. Running for political office. Disarmament sentiments.
Personal and Professional Perspectives 56
Wife and children. Sally Price, champion sailor. Reminiscences of colleagues.