Title and Description Page
Family Background and Childhood in New York 1
Parents emigrate from Russia, meet in New York and marry. Father opens tailor shops. Early education. Interest in radio. Learns to play saxophone.
Columbia University 9
Biology and chemistry classes. Accepts assistantship in biology. Selig Hecht. Doctoral thesis. Presents paper in Leningrad and tour Europe with wife. Collaboration with Simon Shlaer on Warburg's experiments. Begins work on chlorophyll-protein complex.
Cambridge University 27
History of Molteno Institute and parasitology. David Keilin. World War II. Returns to Columbia to work with Pickels.
Rockefeller Institute 33
Colleagues. U.S. entry into World War II. Responsibilities and assignments.
E. R. Squibb & Sons 39
Assists with penicillin research. Frequently asked to solve industry-related problems. Tillman Gerlough.
University of Utah 43
University receives appropriation for muscular dystrophy research. Douglas Brown. Progress in biochemistry and protein chemistry. Serves on first NIH committee on training grants. Makes rounds with medical students. Relationship between biochemistry and medicine.
Authors several textbooks. Serves on University of Utah committees. Children. Principles of Biochemistry.
Peptidase Research 65
Work on the role of metal ions in hydrolytic enzyme reactions. Work on side chain reactions. Colleagues. Financial support. Changes in experimental methods in biochemistry. Role of protein in genetics. Nobel Prize politics.
Immunogobulin Research 75
Work on purification of cow milk antibodies. Immunological experiments during World War II. Decline of interest in intermediary metabolism. Laboratory staff and set-up. Colleagues. Principles of Biochemistry.
Cytochrome Research 84
Develops interest in Keilin's laboratory. Collaboration with Emmanuel Margoliash. Determines sequence of cytochrome c. Origin of interest in evolution.
Subtilisin Research 88
Collaboration with Hiroshi Matsubara on cytochrome c leads to new area of study. Importance of subtilisin to the manufacture of synthetic enzymes.
Histone Research 91
Influence of James Bonner. Colleagues.
Consultation with Industry 94
Squibb—general biochemistry. Proctor & Gamble—subtilisin. Commercial preparations. History of Japanese fermentation industry.
Glutamate Dehydrogenase Research 98
Reasons for beginning work. Chicken enzyme. Neurospora enzyme. Colleagues and students.
Other Activities 100
International Union of Biochemists. Biochemistry section of ACS. Plans international congress. Meets Chou En-lai to discuss scientific exchange between the U.S. and China. Children.